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Serving Size: One Capsule | 60
Adults take 1 capsule daily, 10 minutes prior to physical activity.
Active Ingredients per Serving (1 Capsule - 350mg)
Other Ingredient-HPMC Vegetarian Capsule.
Disclaimer- Contains Caffeine.
Active individuals and elite athletes use caffeine to improve performance. Being alert and having a quick reaction time and increased endurance and energy are vital to any athlete for optimal performance. Caffeine is a well-known ergogenic compound to improve mental focus, alertness, and energy.
Caffeine ingestion prior to exercise increases performance during prolonged endurance exercise and short-term intense exercise lasting ~5 min [1].
Our Formulation
Unived’s Natural Caffeine (200mg) is obtained from Green Tea Extract.
Mode of Action:
1. Caffeine acts in the central nervous system (CNS) as an inhibitor of adenosine thereby inhibiting the negative effects that adenosine induces on neurotransmission (adenosine mediates the perception of drowsiness). Caffeine prevents adenosine from acting and results in alertness and delayed fatigue. This enhances the release of dopamine, serotonin, acetylcholine and GABA. [2], [6].
2. Caffeine increases intracellular concentrations of cyclic adenosine monophosphate (cAMP) by inhibiting phosphodiesterase enzymes in skeletal muscle and adipose tissues. Caffeine also increases adrenaline. These actions promote lipolysis via the activation of hormone-sensitive lipases with the release of free fatty acids and glycerol. The increased availability of these fuels in skeletal muscle acts to spare the consumption of muscle glycogen. This prolongs energy [5].
3. Stimulates calcium release from the sarcoplasmic reticulum during muscle contraction. This increases the strength and duration of contractions in skeletal muscles [2], [6].
References:
1. Spriet, L. L. (1995). Caffeine and Performance, International Journal of Sports Nutrition, 5(s1), S84-S99. Retrieved Nov 30, 2022.
2. Mielgo-Ayuso, Juan, et al. "Effect of caffeine supplementation on sports performance based on differences between sexes: a systematic review." Nutrients 11.10 (2019): 2313.
3. Martins, Gabriel Loureiro, et al. "Caffeine and exercise performance: Possible directions for definitive findings." Frontiers in sports and active living 2 (2020): 574854.
4. Cappelletti S, Piacentino D, Sani G, Aromatario M. Caffeine: cognitive and physical performance enhancer or psychoactive drug? Curr Neuropharmacol. 2015 Jan;13(1):71-88. doi: 10.2174/1570159X13666141210215655. Erratum in: Curr Neuropharmacol. 2015;13(4):554. Daria, Piacentino [corrected to Piacentino, Daria]. PMID: 26074744; PMCID: PMC4462044.
5. Institute of Medicine (US) Committee on Military Nutrition Research. Caffeine for the Sustainment of Mental Task Performance: Formulations for Military Operations. Washington (DC): National Academies Press (US); 2001. 2, Pharmacology of Caffeine.
6. Khan A, Abdalla M A, Zakhary C M, et al. (September 06, 2021) The Relationship Between Caffeine and Caffeinated Drinks in Causing Intracranial Hemorrhage in the Elderly Aspirin-Taking Population: A Systematic Review. Cureus 13(9): e17783. doi:10.7759/cureus.17783
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